Peripheral stimulation affects subthreshold Triple Stimulation Technique

Compared to conventional transcranial magnetic stimulation (TMS), the triple technique (TST) strongly decrease effects of desynchronization descending discharges and accompanying phase cancellation that follow TMS offers a more sensitive method quantify motor evoked potentials (MEPs). Using TST, we explored as whether sub-threshold evokes peripheral neuron (MNs). We compared number MEPs elicited by TST in fifteen healthy participants. used subthreshold intensity 80 % resting threshold. To control assessment corticospinal tract, included condition, which consisted alone, subgroup five volunteers. TMS, at intensities did not detect significantly responses unequivocally attributable cortical stimulation. In contrast, supra-maximal stimuli produced confounding condition were, part, indistinguishable from responses. At intensities, does spinal MNs than and, addition, it is confounded The can be useful assessing integrity MN pool tract. However, if near threshold intensity, need considered; for instance, paired-pulse paradigms physiology.